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SOLID PHASE PEPTIDE SYNTHESIS(SPPS)

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Sunresin Park,No.135, jinye Road, Xi’an Hi-tech Industrial Development Zone, Shaanxi-710076, China
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Solid Phase Peptide Synthesis

Peptide Synthesis Resins

Since Solid Phase Peptide Synthesis was first proposed by Robert Bruce Merrifield, the method of synthetic peptides became more popular than liquid phase peptide synthesis because of high efficiency. This method could assemble a peptide chain rapidly through successive reactions of amino acid derivatives on an insoluble support.
 
Solid Phase Peptide Synthesis-SEPLITE
 
The original peptide antibiotics are also biosynthesized and extracted from the culture of polymyxa or aeruginosa. Another synthetic method of peptides is chemical synthesis, which is divided into liquid phase chemical synthesis and solid phase chemical synthesis. The liquid phase method is mainly used for the synthesis of short peptides. The solid phase synthesis method can be used to prepare long-chain peptides, cyclic peptides, and complex. Peptide. The solid phase method is divided into a Boc method and an Fmoc method. It requires the solid phase synthesis of the carrier to achieve the growth of the peptide chain by means of stepwise amino acid condensation. The advantages of solid phase synthesis are ease of purification, shortening of the synthesis cycle, and ease of automation.

Solid phase peptide synthesis(SPPS) support consists of small, polymeric resin beads functionalized with reactive group such as amine or hydroxyl groups, which link to systhesis peptide chain step by step.

Solid phase peptide synthesis(SPPS) resins is insoluble in all common solvents but swells well in most organic solvents. Better swelling degree is benefit for the reaction yields, but for short peptide easy to synthesis, lower swelling degree will be suitable and it will be good at saving solvent.

Solid phase peptide synthesis Resins are rich in variety, complete in specifications and stable in performance.

Typical Applications

  • Solid phase synthesis of Bivalirudin
  • Solid phase synthesis of Eptifibatide
  • Solid phase synthesis of Exenatide
  • Solid phase synthesis of Liraglutide
  • Solid phase synthesis of thymopentin
  • Solid phase synthesis of Thymalfasin
  • Solid phase synthesis of Buserelin
  • Solid phase synthesis of Goserelin
  • Solid phase synthesis of Octreotide
  • Solid phase synthesis of Calcitonin

Our Customized Service

We also have good experiences in research and develop the amine acid pre-loading peptide resins, and we have extended resin backbone to hydrophilic matrix, such as DEG series, TEG series, PEG series. Welcome to ask for Sunresin!

 

Our Product List
Bio-Pharmaceutical & Life Science
Modern biopharmaceutical technologies typically use biological microbial fermentation...
Chemical Industry
Purification of chemical compounds has become a vital part of most industrial processes.
Drinking Water Treatment
Drinking water is essential to life. Every day every human being has to drink and use water for food preparation.
Food & Beverage Industries
Food is closely related to everyone, and the finishing of food comes from people's relentless pursuit...
Hydrometallurgy & Mining
Hydrometallurgy is a technique for extractive metallugry involving the three general area...
Direct Lithium Extraction (DLE)
Sunresin is the major DLE lithium sorbent producer in China which mainly used for extraction lithium from salar brine and geothermal brine etc with high efficiency.
Industry Water Treatment
There are many uses of water in industry and, in most cases, the used water also needs treatment to render...
Plant Extraction
Plant Extraction is a process to gather the trace bioactive compounds from the tissue of a plant.
VOCs Treatment
With the widespread use of chemical products in the industry, more and more organic...
Wastewater Treatment
Wastewater treatment is the process of converting wastewater into an effluent that can be discharged
Latest News
30
2024 08
 Sunresin Makes Hurun China Top 500 List
The Hurun Research Institute recently released their "2023 Hurun China Top 500" list, with Sunresin has making the list in recognition of its outstanding market performance and innovation capabilities. This is the only company on the list in China's adsorption separation materials industry.
22
2024 06
 Exhibition Highlights | Sunresin Showcases at SIWW 2024 Singapore International Water Week
From June 19-21, 2024, the Singapore International Water Week (SIWW Water Expo 2024) was held at the Marina Bay Sands Expo and Convention Centre in Singapore. Sunresin showcased its internationally leading products and technologies at the event.
10
2024 05
 Sunresin and Latin America: Ten thousand miles are still neighbors
In April, Ambassador Xu Yicong's book launch of "Family and Country Sentiments - Continuing Chapter" was successfully held in Beijing. The ambassadors of Latin America in China have come to congratulate Ambassador Xu, and Zhai Feng, Vice President of Bump Cycle, attended to celebrate the event. Dr. Gao Yuejing, as the representative of the important guests, gave a speech and expressed her most sincere blessing to Ambassador Xu for the publication of his new book.
Here to Provide Complete Separation and Purification Solutions
Sunresin Park,No.135, jinye Road, Xi’an Hi-tech Industrial Development Zone, Shaanxi-710076, China
Call us on:
+86-29-89182091
8615619222154
+86-29-89182091
seplite@sunresin.com