The ion exchange resin causes degradation of the functional group and a decrease in the exchange capacity at a certain temperature, so the use of the resin needs to be maintained at a certain temperature as much as possible.

Polypeptide synthesis on a solid support, a concept of originality pioneered by Robert Bruce M errifield in 1963, is a major breakthrough in peptide chemistry.

The Boc/Bzl (tert-butoxycarbonyl/ /benzyl) method is a classical peptide solid phase synthesis method in which Boc is used as a temporary protecting group in combination with a benzylic semi-permanent side chain protecting group.

The Fmoc method is a new method for solid phase synthesis of peptides developed by Carpino and Hart based on the Boc method.

1. Cephalosporin C Also known as CPC (cephalosporin C, M = 415.44), it is an antibiotic produced by a fungus of the genus Cephalospores close to penicillin. Cephalosporin C is a raw material for the production of 7-aminocephalosporanoic acid (7-ACA, 7-aminocephalospranic acid, M=272.28), and 7-ACA is an important raw material for many synthetic cephalosporin antibiotics.

1. Vitamin B12 Known as cobalamin. It is a water-soluble vitamin that participates in various metabolisms in the form of coenzymes and promotes DNA and protein synthesis. 2. Synthesis of vitamin B12 The chemical synthesis of vitamin B12 is costly and the by-products are also more. At present, the mainstream is the fermentation method.

Adipic acid is an important chemical raw material, mainly producing nylon 66.

1. Electronic grade hydrogen peroxide. Hydrogen peroxide can be used in the semiconductor industry.